B2B Payments Now Drive Stablecoin Growth, Surpassing Peer-to-Peer Use: Artemis Report

Business-to-business (B2B) transactions have emerged as the fastest-growing use case for stablecoins, according to a new survey by blockchain analytics firm Artemis, co-authored with investment firms Castle Island Ventures and Dragonfly Ventures.
This trend marks a significant shift in the stablecoin landscape, long dominated by peer-to-peer (P2P) activity.
$3 Billion in Monthly B2B Flows
The report reveals that monthly B2B stablecoin volumes exceeded $3 billion by early 2025, a dramatic rise from less than $100 million in early 2023. This growth translates to an estimated $36 billion annual run rate, driven by rising demand for vendor payments, collateral transfers, and cross-border settlements.
Rising Industry Focus
The findings are based on a survey of 31 global stablecoin payment firms, many of which are increasingly focused on the B2B segment. New entrants such as Bitso Business, Conduit, and Yellow Card — Africa’s first and largest licensed stablecoin firm — are building infrastructure tailored specifically for enterprise use.
Other Stablecoin Use Cases
While B2B transactions are surging, peer-to-peer transfers remain the second-largest category. An emerging third segment is stablecoin card payments, where users link prepaid or debit cards to blockchain wallets to spend stablecoins directly.
This evolution reflects the growing maturity of stablecoins as a payment and settlement layer for the global economy, with enterprise adoption now at the forefront of sector growth.